Listar por autor "Blanco Luquin, Idoia"
Mostrando ítems 1-11 de 11
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Association of blood-based DNA methylation markers with late-onset alzheimer disease: a potential diagnostic approach
Acha Santamaría, Blanca
; Corroza, Jon; Sánchez Ruiz de Gordoa, Javier ; Cabello, Carolina; Robles Solano, Maitane; Méndez López, Iván ; Macías, Mónica; Zueco, Sara; Roldán, Miren; Urdánoz Casado, Amaya ; Jericó Pascual, Ivonne; Erro Aguirre, María Elena; Alcolea, Daniel; Lleo, Alberto; Blanco Luquin, Idoia; Mendióroz Iriarte, Maite (Lippincott Williams & WilkinsAmerican Academy of Neurology, 2023)
Artículo / Artikulua 
Background and Objectives: There is an urgent need to identify novel noninvasive biomarkers for Alzheimer disease (AD) diagnosis. Recent advances in blood-based measurements of phosphorylated tau (pTau) species are promising ... -
CDH22 hypermethylation is an independent prognostic biomarker in breast cancer
Martín Sánchez, Esperanza; Mendaza Lainez, Saioa; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Blanco Luquin, Idoia; Cruz, Susana de la; Aramendia, Ana; Guerrero Setas, David (BioMed Central, 2017)
Artículo / Artikulua
Background: Cadherin-like protein 22 (CDH22) is a transmembrane glycoprotein involved in cell-cell adhesion and metastasis. Its role in cancer is controversial because it has been described as being upregulated in ... -
Changes in gene expression profiling of apoptotic genes in neuroblastoma cell lines upon retinoic acid treatment
Celay Leoz, Ion; Blanco Luquin, Idoia; Lázcoz, Paula ; Rotinen Díaz, Mirja Sofia ; Castresana, Javier S.; Encío Martínez, Ignacio (Public Library of Science, 2013)
Artículo / Artikulua
To determine the effect of retinoic acid (RA) in neuroblastoma we treated RA sensitive neuroblastoma cell lines with 9-cis RA or ATRA for 9 days, or for 5 days followed by absence of RA for another 4 days. Both isomers ... -
CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer
Martín Sánchez, Esperanza; Mendaza Lainez, Saioa; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Blanco Luquin, Idoia; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Pérez Janices, Noemi; Escors Murugarren, David; Megías, Diego (Impact Journals, 2017)
Artículo / Artikulua
The CHL1 gene encodes a cell-adhesion molecule proposed as being a putative tumour-suppressor gene in breast cancer (BC). However, neither the underlying molecular mechanisms nor the clinical value of CHL1 downregulation ... -
Circular RNA expression profile in blood according to ischemic stroke etiology
Ostolaza, Aiora; Blanco Luquin, Idoia; Urdánoz Casado, Amaya ; Rubio, Idoya; Labarga, Alberto (BioMed Central, 2020)
Artículo / Artikulua
Background: The discovery of novel biomarkers of stroke etiology would be most helpful in management of acute ischemic stroke patients. Recently, circular RNAs (circRNAs) have been proposed as candidate biomarkers of ... -
Gender-dependent deregulation of linear and circular RNA variants of homer1 in the entorhinal cortex of Alzheimer’s disease
Urdánoz Casado, Amaya ; Sánchez Ruiz de Gordoa, Javier ; Robles Solano, Maitane; Acha Santamaría, Blanca ; Roldán, Miren; Zelaya Huerta, María Victoria ; Blanco Luquin, Idoia; Mendióroz Iriarte, Maite (MDPI, 2021)
Artículo / Artikulua
The HOMER1 gene is involved in synaptic plasticity, learning and memory. Recent studies show that circular RNA derived from HOMER1 (circHOMER1) expression is altered in some Alzheimer’s disease (AD) brain regions. In ... -
Identificación de biomarcadores epigenéticos de metilación del DNA en la sangre periférica de pacientes con enfermedad de Alzheimer
Acha Santamaría, Blanca (2024)
Tesis doctoral / Doktoretza tesia
En esta tesis doctoral, se investiga el papel de la metilación del DNA como un potencial biomarcador diagnóstico de la EA, dada la novedad que los mecanismos epigenéticos han supuesto en la búsqueda de biomarcadores en la ... -
Identificación de circRNAs como biomarcadores epigenéticos candidatos en la enfermedad de Alzheimer
Urdánoz Casado, Amaya (2022)
Tesis doctoral / Doktoretza tesia
La enfermedad de Alzheimer (EA) es una enfermedad neurodegenerativa, crónica y, por el momento, irreversible que representa la primera causa de demencia relacionada con la edad. Su diagnóstico sigue siendo un reto. En los ... -
In vitro assessment of the role of p53 on chemotherapy treatments in neuroblastoma cell lines
Blanco Luquin, Idoia; Lázcoz, Paula; Celay Leoz, Ion ; Castresana, Javier S.; Encío Martínez, Ignacio (MDPI, 2021)
Artículo / Artikulua
Neuroblastoma is the most frequent malignant extracranial solid tumor of infancy. The overall objective of this work consists of determining the presence of alterations in the p53/MDM2 /p14ARF signaling pathway in neuroblastoma ... -
NXN gene epigenetic changes in an adult neurogenesis model of Alzheimer's disease
Blanco Luquin, Idoia; Acha Santamaría, Blanca ; Urdánoz Casado, Amaya ; Gómez Orte, Eva; Roldán, Miren; Pérez Rodríguez, Diego R.; Cabello, Juan; Mendióroz Iriarte, Maite (MDPI, 2022)
Artículo / Artikulua
In view of the proven link between adult hippocampal neurogenesis (AHN) and learning and memory impairment, we generated a straightforward adult neurogenesis in vitro model to recapitulate DNA methylation marks in the ... -
Profile of TREM2-derived circRNA and mRNA variants in the entorhinal cortex of Alzheimer's disease patients
Urdánoz Casado, Amaya; Sánchez Ruiz de Gordoa, Javier; Robles, Maitane; Roldán, Miren; Zelaya Huerta, María Victoria ; Blanco Luquin, Idoia; Mendióroz Iriarte, Maite (MDPI, 2022)
Artículo / Artikulua
Genetic variants in TREM2, a microglia-related gene, are well-known risk factors for Alzheimer’s disease (AD). Here, we report that TREM2 originates from circular RNAs (circRNAs), a novel class of non-coding RNAs ...
